Susan and Mike try to name their son. Mike wants to name him after his deceased grandfather, Maynard. Lynette is arrested for child abuse of Kayla. Bree is being stalked by Orson, and when she meets with Reverend Green (guest star Bill Smitrovich), the reverend tries to hit on her. Gabrielle is still helping the police trying to detain Ellie (guest star Justine Bateman) for dealing drugs. Katherine is visited by her ex-husband, Wayne (guest star Gary Cole), who wants to know why Dylan doesn’t have a childhood scar on her arm anymore.
After Katherine announces that she has to leave town, Bree is left responsible for catering Bob and Lee’s wedding. Gabrielle finds $118,000 in Ellie’s teddy bear. Susan realizes she will soon lose someone she loves. Katherine Mayfair’s secrets are finally revealed, and several residents of Wisteria Lane are faced with deadly threats.
Adele Delfino (guest star Celia Weston), Susan’s mother-in-law, arrives for a visit. Carlos and Gabrielle find out their tenant, Ellie (guest star Justine Bateman), has a dark secret. Lynette has more problems with Kayla. A full scale war erupts between Bree and Edie.
Susan meets her ex-husband, Karl (guest star Richard Burgi) at a Lamaze class, and finds out that he has remarried and is having another child. Lynette learns who was responsible for starting the fire at Rick’s restaurant. Bree wants Orson to turn himself in to the police. Gabrielle rents a room to a hip artist, Ellie (guest star Justine Bateman), who has a dark secret. Dylan continues meeting with her father, Wayne (guest star Gary Cole), and Katherine decides to go spy on her.
Bree and Katherine decide to start a catering business together. Lynette tries to deny her feelings for Rick (guest star Jason Gedrick). Mike learns the truth about his nearly fatal accident. Carlos gets a seeing-eye dog. Dylan meets her estranged father (guest star Gary Cole).
Bree and Katherine join forces to plan the Founders’ Day Ball. Lynette is surprised when Rick (guest star Jason Gedrick) shows up at the Scavo pizzeria. Gabrielle struggles with the reality of having a blind husband. Mike asks Orson for forgiveness as part of his recovery program, and Orson starts sleepwalking.